The Scuola Grande di San Rocco, was dedicated to the protector of  plague vicitms. It is a beautiful Rennaissance building whose interiori s rich with works of art by Tintoretto,  Giorgione, Tiziano, Giambattista Tiepolo  and wooden sculptures by Francesco Pianta.

The Church was founded at the beginning of the 15th century and houses many 14th and 15 century works of art including Tintoretto, Ricci e Pordenone.

Saint Rocco Church, nowadays an orthodox Romanian parish, was erected in 1476 by order of some merchants living in Mestre. It was meant as a vow during a terrible plague. Originally the church hosted three confraternities: St Rocco, consecrated to the assistance of the infected, St Francesco di Paolo and Antonio di  Padova, both charity orders.